Rate of sequence divergence under constant selection
نویسندگان
چکیده
منابع مشابه
Population genetics of polymorphism and divergence under fluctuating selection.
Current methods for detecting fluctuating selection require time series data on genotype frequencies. Here, we propose an alternative approach that makes use of DNA polymorphism data from a sample of individuals collected at a single point in time. Our method uses classical diffusion approximations to model temporal fluctuations in the selection coefficients to find the expected distribution of...
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The genome sequences of multiple species has enabled functional inferences from comparative genomics. A primary objective is to infer biological functions from the conservation of homologous DNA sequences between species. A second, more difficult, objective is to understand what functional DNA sequences have changed over time and are responsible for species' phenotypic differences. The neutral ...
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Given a lossless view associating a source relation with a set of target relations defined by selection queries over the source, we study how updates of the target relations can be consistently and univocally propagated to the underlying source relation. We consider a setting where some of the attributes in the schema are interpreted over some specific domain (e.g., the reals or the integers) w...
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Given a lossless view associating a source relation with a set of target relations defined by selection queries over the source, we study how updates of the target relations can be consistently and univocally propagated to the underlying source relation. We consider a setting where some of the attributes in the schema are interpreted over some specific domain (e.g., the reals or the integers) w...
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MOTIVATION A number of statistical phylogenetic methods have been proposed to identify type-I functional divergence in duplicate genes by detecting heterogeneous substitution rates in phylogenetic trees. A common disadvantage of the existing methods is that autocorrelation of substitution rates along sequences is not modeled. This reduces the power of existing methods to identify regions under ...
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ژورنال
عنوان ژورنال: Biology Direct
سال: 2010
ISSN: 1745-6150
DOI: 10.1186/1745-6150-5-5